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A systematic review published in 2022 that combined the results of 23 studies found that people taking 2.4 milligrams of semaglutide lost an average of 27.4 pounds. People taking 3 milligrams of liraglutide lost an average of 11.5 pounds. Additionally, the FDA removed tirzepatide from its drug shortage list in early October 2024, and it removed semaglutide from the list in February 2025. As such, it is no longer legal for pharmacies to make the compounded drugs as of May 22,...